This week: Giant otters, axolotls and new pain killers.
An otter the size of a wolf that lived 6 million years ago may have been a dominant predator. A new analysis indicates that it had a much more powerful bite than anticipated.
Axolotls, the Mexican salamander (pictured), are a favoured model organism because of their astonishing ability to regenerate their limbs. They are also popular pets. Unfortunately, they are heading towards extinction in the wild.
Not exactly news, but certainly topical: Nature videos has produced an excellent animation detailing how CRISPR/Cas9 gene editing works, and the potential useful modifications, including some newer ones I detailed in a recent post on gene editing.
The opioid epidemic in the US is causing several thousand deaths a year. These drugs give powerful pain relief, but have the side-effect of suppressing breathing: fatal overdoses usually kill because the person stops breathing. So many research groups are designing drugs that preferentially cause the pain relief without the respiratory depression, and a new paper in Cell this week (link to perspective article) identifies some possibilities that could be even more effective than those currently in clinical trials. This is behind the paywall, unfortunately, but there’s a news piece here.