biology, Developmental biology, Organ transplantation, Science, science news, Sunday Science Stories

Sunday Science 18/02/2018

Welcome to this week’s Sunday Science, with self-reproducing crayfish, breakthroughs in developmental biology, the quantum internet, and cleaning.

A big story that’s just hit the mainstream news: scientists have managed to grow sheep embryos containing human cells: 1/10,000 of the sheep embryo’s cells were human, after 28 days of development. This offers the potential of radically improving transplants, and builds on the group’s previous success with pig embryos, but with tenfold efficiency.

An invasive crayfish spreading through Madagascar is a recent hybrid species that reproduces through parthenogenesis – as in, without mating, with the unfertilised egg developing into an adult by itself.

Researchers have found a way to artificially treat wood,compressing it in a way that substantially increases its strength and stiffness and offers more engineering possibilities for this sustainable (when managed) material.

The axolotl genome has been sequenced (open access: technical). The Mexican salamander, as it is also known, is an important model in developmental biology, with scientists keen to understand how it can regenerate it’s limbs. Already the genome has thrown up a lot of information and a few surprises: it lacks a key gene, Pax3, that is essential in other vertebrates.

Still on the subject of developmental biology: scientists are attempting to create a “human developmental cell atlas” – mapping the development of humans from embryos at a single cell level (open access, bit technical). This is in conjunction with the Human Cell Atlas, here, and made possible by modern molecular methods that allow us to minutely examine which genes are active in which cells.

A nice piece on the future of the (potential) quantum internet, long theorised by both science fiction authors and scientists.

And finally: women who do lots of cleaning at home have a greater risk of decline in lung function. Men don’t, apparently, so clearly they should be doing all the cleaning!

Featured image

Part of an experiment to investigate diamond-based systems as quantum-internet nodes at Delft University of Technology in the Netherlands. Credit: Marcel Wogram for Nature

biology, Developmental biology, evolution, genetic modification, Miscellaneous, Science, Science and society, science news, SF and science, Sunday Science Stories

Sunday Science 01/10/17

Here is the this week’s Sunday Science, including truly wearable tech, tsunami-borne sea creatures and duck penises.

Do you have one of those smartwatches which measures your heart rate when you exercise? Does your smartphone automatically keep track of how many steps you take each day. Well, the future both for this and for medical monitoring may lie more in flexible, wearable sensors, or the bodynet, as this fascinating piece in Nature of the latest merging of scifi with science fact explores.

Male ruddy ducks regenerate their penis every year, apparently, one of those glorious facts you never knew you needed in your life. However, they may grow an extra-long (as in, 18cm!) or an extra-short one (only 0.5cm), due to fierce sexual competition.

Salmon have returned to a river in Derbyshire for the first time since the Industrial Revolution.

Continuing the CRISPR revolution, it has been used to genetically engineer human embryos to study early embryo development, revealing an important role for a gene in embryo implantation and miscarriage risk.

This week’s featured image is of marine sea slugs from a Japanese vessel from Iwate Prefecture, washed ashore in Oregon in April 2015 [Image credit Mark Chapman via Science Daily]. Thousands of creatures were washed across the ocean as a consequence of the Japanese tsunami, a study published in Science magazine discovered. Such “rafting” events are natural, of course, but what’s not natural is the extent of this migration, much of which was enabled by animals riding along on our non-degradable plastic waste. Nearly 300 species have appeared on the west coast of the US and Hawaii. This is potentially setting in motion a radical ecological experiment.

biology, Developmental biology, genetic modification, medicine, Science

Genetically engineered human embryos have arrived

Well, it was only a matter of time. All the major news outlets are reporting the breakthrough of a research team that managed to use CRISPR/Cas9 to edit human embryos that carried a mutation which causes cardiac hypertrophy (MYBPC3) – a thickening of the heart muscle that is the leading cause of death in young atheletes. Continue reading

biology, Developmental biology, Explainer, Opinion piece, Science, Science and society, SF and science

Will we ever have artificial wombs?

A few years back I attended the annual conference of the British Society for Developmental Biology. There was a discussion session towards the end of the day concerning future developments and directions in our field of research, namely how one goes from the early embryo to, ultimately, the adult human (or other organism). Into a lull in the conversation, my then-boss, who was heavily pregnant with twins and very uncomfortable, interjected the following question: “I only want to know one thing right now: when are we going to be able to grow babies in artificial wombs?” Good question…

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biology, Developmental biology, evolution, Science

Meanings in a song: Australian finches tell their chicks about the world outside the egg

I had one of those “I never knew that,” moments reading a paper in Science magazine this week, but, given that the research in question managed to get published in one of the top journals in the field, neither did lots of other people. The “that” in question? That sounds can alter the development of a embryonic bird to enable it to adapt to the environment it can expect when it hatches. Continue reading

biology, Developmental biology, Explainer, genetic modification, Opinion piece, Organ transplantation, Science

Growing human organs: we’re closer than you think

(Edit note: I somehow disappeared this whilst correcting an image, so if it’s still problematic, drop me a note!)

One of the major medical advances of the last century was that of organ transplantation: replacing diseased organs with healthy ones from donors (usually the recently dead, but there are exceptions: you can donate one kidney, or parts of your liver, for example). It is a process that has become ever more successful, with improvements in surgery and drugs that suppress the immune system, preventing it from destroying the donated organ. However, this has created a demand for donor organs that is not being met: about 100,000 people worldwide are waiting for donor organs, and many thousands die before they receive one. Continue reading