biology, Explainer, medicine, News, Opinion piece

Zika virus: from mice to monkeys, via organoids

There’s been a rush of new papers out lately which are starting to explain how Zika virus causes fetal damage. Understandably, since the suspicion of a link between Zika and microcephaly (an abnormally small head, associated with neurological defects) in humans was raised, there’s been an intensive research effort directed at uncovering the causality of this process, but I’m still impressed at the speed at which scientists are gaining answers. It was only last month, after all, that the CDC declared that there was a “causal link” between Zika and microcephaly. Continue reading

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biology, Developmental biology, Explainer, genetic modification, Opinion piece, Organ transplantation, Science

Growing human organs: we’re closer than you think

(Edit note: I somehow disappeared this whilst correcting an image, so if it’s still problematic, drop me a note!)

One of the major medical advances of the last century was that of organ transplantation: replacing diseased organs with healthy ones from donors (usually the recently dead, but there are exceptions: you can donate one kidney, or parts of your liver, for example). It is a process that has become ever more successful, with improvements in surgery and drugs that suppress the immune system, preventing it from destroying the donated organ. However, this has created a demand for donor organs that is not being met: about 100,000 people worldwide are waiting for donor organs, and many thousands die before they receive one. Continue reading