biology, evolution, genetic modification, medicine, Organ transplantation, Robotics, Science, science news

Sunday Science 12/11/17

Welcome to this week’s Sunday Science, with skin regeneration, bees and pesticides, evolving bacterial ecosystems, and sensitive robot skin.

First up, a major breakthrough which did make the mainstream news was the story of a boy with a lethal condition which had resulted in the loss of most of his skin, who had genetically engineered skin grafts (pictured) and is now living essentially a normal life. There’s a Nature opinion piece here which has a more scientific slant, putting this research in context. The original research article is here, and open access (be warned it has a distressing photo of the child pre-treatment). Although extremely rare, these genetic diseases do affect nearly half a million people worldwide, and are agonising and often fatal.

 

I’ve blogged before about  “soft robotics” inspired by biology. A couple of stories I missed earlier include this piece on an artificial “skin” for robots that can be stretched and detect vibration and shear forces, crucial for handling objects. Also, other scientists have developed robotic skin that can change shape and colour, inspired by cephalopods, which is rather cool. (Research article may be found here, but it’s behind the Science paywall).

There has been an ongoing long-term experiment observing thousands of generations of the bacteria E.coli, to observe evolution in action. The latest results reveal that – even in bacteria – ecological interactions arise spontaneously, and the bacteria form little specialised sub-populations. Link is to an opinion piece; the full-text article link can be found from that for the technically minded.

There’s been a lot in the press recently about calls to ban neonicotinoid pesticides. The UK has long resisted efforts in the EU to ban them – now it seems that it will push for a full ban.  There’s a thoughtful opinion piece here that weighs up the evidence behind this. (I should note a disclaimer in that Prof Dave Goulson, quoted in the piece, works at my institution).

 

Photo: Nature Press.

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biology, medicine, Organ transplantation, Robotics, Science, SF and science

The future of artificial limbs

I’ve written on this blog before about how advances in our understanding and application of genetic engineering and stem cell technology is raising the realistic possibility of growing replacement human organs. What I haven’t really covered is replacing limbs. This is a somewhat different proposition: if we grew human organs in a dish (so to speak), we’d transplant them into the people that needed them. These kinds of transplant operations now have a substantial surgical history and practice behind them, so it wouldn’t require the development of new techniques. Replacing limbs, however, does not: people have instead relied on artificial prostheses. These are a staple of science fiction too: from Luke Skywalker to the 6 million dollar man to Robocop, prosthetics and – at the extreme end – full human “cyborgs” are everywhere. Replacing limbs with actual biological limbs, however, well…the first thing that springs to mind is Frankenstein, which is unfortunate. There are a few scifi societies where regrowing replacement limbs is the norm (notably lain M Banks’ Culture) but scifi seems to think prostheses are the future, as they are our present. But are they?

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biology, Developmental biology, Explainer, genetic modification, Opinion piece, Organ transplantation, Science

Growing human organs: we’re closer than you think

(Edit note: I somehow disappeared this whilst correcting an image, so if it’s still problematic, drop me a note!)

One of the major medical advances of the last century was that of organ transplantation: replacing diseased organs with healthy ones from donors (usually the recently dead, but there are exceptions: you can donate one kidney, or parts of your liver, for example). It is a process that has become ever more successful, with improvements in surgery and drugs that suppress the immune system, preventing it from destroying the donated organ. However, this has created a demand for donor organs that is not being met: about 100,000 people worldwide are waiting for donor organs, and many thousands die before they receive one. Continue reading