biology, cancer, evolution, immunotherapy, Robotics, Science, science news, Sunday Science Stories

Bionic limbs, Bronze Age baby feeding, whale evolution, immunotherapy & more: Sunday Science 06/10/19

Welcome to this week’s Sunday Science, featuring a successful immunotherapy trial for advanced melanoma, sensitive prosthetic limbs, Bronze age baby bottles, an intriguing study of genetic adaptation in whales and dolphins, dreaming octopuses and one incredibly tough little worm… Continue reading

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Biological therapy, cancer, immunotherapy, science news, Uncategorized

Immunotherapy in the news again

It’s been a busy couple of weeks, with a teething baby eating my sleep and job applications eating my time, so a longer written piece is off the cards for now. It seems my piece on new cancer treatments, specifically immunotherapy, however, was a timely one, as it’s hitting the news again, with big successes reported in the use of modified T-cell therapy to treat blood cancers, reported in the Guardian here. These include some startling trial results:

In the most promising study, about 35 patients with ALL were treated with Cars-modified T-cells; 94% went into remission, though symptoms could reappear. More than 40 patients with lymphoma have also been treated, with remission rates of more than 50%. In a group with non-Hodgkin’s lymphoma, there was evidence of diminished cancer symptoms in more than 80% of cases.

These are really impressive figures. Is it just hype? These results were reported at a major scientific meeting, and the ALL (acute lymphoblastic leukaemia) trial results are described as being under review and pending publication. So it’s not just a press release from a laboratory that has been wildly spun out of all proportion by an over-enthusiastic press. I for one will definitely be wanting to read the original research paper when (if) it is published. We can expect to see a flood of trial results and papers published within the next couple of years, if it lives up to even half of its original promise.