biology, genetic modification, Opinion piece

Some thoughts on genome editing

I remember back in around 2007, the head of the lab I was currently working in jetted in (literally; he had been on the other side of the world) in a flurry of excitement about a new technique he wanted to roll out comprehensively to engineer mutations in the lab’s model organism of choice, the zebrafish. The technique involved the use of zinc finger nucleases, and he thought it would revolutionise the whole tricky business of trying to introduce mutations into the genome (i.e. so they could be inherited by any offspring) of model organisms. He was half-right.

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